611-71-2
- Product Name：Mandelic acid
- Molecular Formula：C8H8O3
- Purity：99%
- Molecular Weight：152.15
Product Details
Factory Sells Best Quality Mandelic acid 611-71-2 with GMP standards
- Molecular Formula:C8H8O3
- Molecular Weight:152.15
- Appearance/Colour:white to light yellow crystal powder
- Vapor Pressure:5.14E-05mmHg at 25°C
- Melting Point:131-133 °C(lit.)
- Refractive Index:-153.5 ° (C=1, H2O)
- Boiling Point:321.8 °C at 760 mmHg
- PKA:3.37(at 25℃)
- Flash Point:162.6 °C
- PSA：57.53000
- Density:1.321 g/cm3
- LogP:0.80460
Mandelic acid(Cas 611-71-2) Usage
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Synthesis Reference(s) |
The Journal of Organic Chemistry, 33, p. 2565, 1968 DOI: 10.1021/jo01270a105Synthetic Communications, 18, p. 2141, 1988 DOI: 10.1080/00397918808068285 |
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Flammability and Explosibility |
Nonflammable |
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General Description |
(R)-(-)-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (R,S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme. |
InChI:InChI=1/C9H10O3/c1-6(10)7-4-2-3-5-8(7)9(11)12/h2-6,10H,1H3,(H,11,12)/t6-/m1/s1
611-71-2 Relevant articles
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Lewkowitsch
, p. 1574,2722 (1883)
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Enantioseparation of Mandelic Acid Enantiomers with Magnetic Nano-Sorbent Modified by a Chiral Selector
Tarhan, Tuba,Tural, Bilsen,Tural, Servet,Topal, Giray
, p. 835 - 842 (2015)
In this study, R(+)-α-methylbenzylamine-...
Process Development for the Production of (R)-(-)-Mandelic Acid by Recombinant Escherichia coli Cells Harboring Nitrilase from Burkholderia cenocepacia J2315
Wang, Hualei,Fan, Haiyang,Sun, Huihui,Zhao, Li,Wei, Dongzhi
, p. 2012 - 2016 (2015)
(R)-(-)-Mandelic acid is an important ch...
An organic solvent and thermally stable lipase from Burkholderia ambifaria YCJ01: Purification, characteristics and application for chiral resolution of mandelic acid
Yao, Changjin,Cao, Yan,Wu, Shanshan,Li, Shuang,He, Bingfang
, p. 105 - 110 (2013)
A solvent-tolerant bacterium Burkholderi...
Highly efficient resolution of mandelic acid using lipase from Pseudomonas stutzeri LC2-8 and a molecular modeling approach to rationalize its enantioselectivity
Cao, Yan,Wu, Shanshan,Li, Jiahuang,Wu, Bin,He, Bingfang
, p. 108 - 113 (2014)
Mandelic acid, a key precursor of chiral...
R-mandelic acid production with immobilized recombinant Escherichia coli cells in a recirculating packed bed reactor
Zhang, Xin-Hong,Liu, Zhi-Qiang,Xue, Ya-Ping,Yang, Bo,Xu, Ming,Zheng, Yu-Guo
, p. 205 - 211 (2016)
A recirculating packed bed reactor (RPBR...
Optical Resolution of Phenylalanine and Mandelic Acid
Yamamoto, Yasushi,Kato, Shinji,Yamashita, Hiroshi,Maekawa, Takashi
, p. 3149 - 3152 (1992)
The optical resolutions of phenylalanine...
Screening for enantioselective nitrilases: Kinetic resolution of racemic mandelonitrile to (R)-(-)-mandelic acid by new bacterial isolates
Kaul, Praveen,Banerjee, Anirban,Mayilraj,Banerjee, Uttam C.
, p. 207 - 211 (2004)
Several new microorganisms have been iso...
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Ingersoll,Babcock,Burns
, p. 411,414 (1933)
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Woehler
, p. 240 (1848)
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Surface functionalization of chitosan-coated magnetic nanoparticles for covalent immobilization of yeast alcohol dehydrogenase from Saccharomyces cerevisiae
Li, Gui-Yin,Zhou, Zhi-De,Li, Yuan-Jian,Huang, Ke-Long,Zhong, Ming
, p. 3862 - 3868 (2010)
A novel and efficient immobilization of ...
Nucleation and growth kinetics of (R)-mandelic acid from aqueous solution in the presence of the opposite enantiomer
Zhang, Yan,Mao, Shimin,Ray, Ajay K.,Rohani, Sohrab
, p. 2879 - 2887 (2010)
Resolution of mandelic acid (MA), a race...
Constituents of Prunus zippeliana leaves and branches
Kitajima,Tanaka
, p. 2007 - 2009 (1993)
The following substances were identified...
Improvement of alcaligenes faecalis nitrilase by gene site saturation mutagenesis and its application in stereospecific biosynthesis of (R)-(-)-mandelic acid
Liu, Zhi-Qiang,Zhang, Xin-Hong,Xue, Ya-Ping,Xu, Ming,Zheng, Yu-Guo
, p. 4685 - 4694 (2014)
Nitrilases have recently received consid...
Gene cloning, expression, and characterization of a nitrilase from Alcaligenes faecalis ZJUTB10
Liu, Zhi-Qiang,Dong, Li-Zhu,Cheng, Feng,Xue, Ya-Ping,Wang, Yuan-Shan,Ding, Jie-Nv,Zheng, Yu-Guo,Shen, Yin-Chu
, p. 11560 - 11570 (2011)
Nitrilases are important industrial enzy...
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Marckwald,Mc Kenzie
, (1901)
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Synthesis of α-hydroxycarboxylic acids from various aldehydes and ketones by direct electrocarboxylation: A facile, efficient and atom economy protocol
Singh, Kishanpal,Sohal, Harvinder Singh,Singh, Baljit
, p. 839 - 845 (2021/04/09)
In present work, the formation of α-hydr...
Designing of amino functionalized imprinted polymeric resin for enantio-separation of (±)-mandelic acid racemate
Alhawiti, Aliyah S.,Monier,Elsayed, Nadia H.
, (2021/02/12)
S-Mandelic acid (MA) enantio-selective r...
High-yield DL-mandelic acid synthesis process
-
, (2021/09/04)
The invention provides a high-yield DL-m...
Method for synthesizing mandelic acid
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Paragraph 0032; 0034-0035; 0037-0038; 0040-0041; 0043, (2021/02/06)
The invention relates to the technical f...
611-71-2 Process route
-
-
4542-46-5
2-(morpholin-4-yl)ethanethiol
-
-
1075-06-5
2,2-dihydroxy-1-phenyl-ethanone
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611-71-2,611-72-3,17199-29-0,90-64-2
MANDELIC ACID
| Conditions | Yield |
|---|---|
|
With
water;
|
-
-
56-23-5
tetrachloromethane
-
-
4393-06-0
1-Phenyl-2-propen-1-ol
-
-
64-18-6
formic acid
-
-
611-71-2,611-72-3,17199-29-0,90-64-2
MANDELIC ACID
-
-
65-85-0,8013-63-6
benzoic acid
| Conditions | Yield |
|---|---|
|
beim Ozonisieren;
|
611-71-2 Upstream products
-
4542-46-5
2-(morpholin-4-yl)ethanethiol
-
1075-06-5
2,2-dihydroxy-1-phenyl-ethanone
-
56-23-5
tetrachloromethane
-
4393-06-0
1-Phenyl-2-propen-1-ol
611-71-2 Downstream products
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6454-27-9
2-methyl-5-phenyl-[1,3]dioxolan-4-one
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66267-71-8
mandelic acid-tetrahydrofurfuryl ester
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1759-00-8
2-hydroxy-2-phenyl-N-(pyridin-2-yl)acetamide
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1026-26-2
N-(5-methyl-[2]pyridyl)-mandelamide
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