
99-97-8
- Product Name:N,N-Dimethyl-p-toluidine
- Molecular Formula:C9H13N
- Purity:99%
- Molecular Weight:135.209
Product Details
Chinese Manufacturer supply N,N-Dimethyl-p-toluidine 99-97-8 in stock with high standard
- Molecular Formula:C9H13N
- Molecular Weight:135.209
- Appearance/Colour:light yellow liquid
- Vapor Pressure:0.1 hPa (20 °C)
- Melting Point:-25°C
- Refractive Index:n20/D 1.546(lit.)
- Boiling Point:211.6 °C at 760 mmHg
- PKA:pK1:7.24(+1) (25°C)
- Flash Point:84.2 °C
- PSA:3.24000
- Density:0.94 g/cm3
- LogP:2.06100
N,N-DIMETHYL-P-TOLUIDINE(Cas 99-97-8) Usage
Synthesis Reference(s) |
Synthetic Communications, 19, p. 3051, 1989 DOI: 10.1080/00397918908052700Tetrahedron Letters, 8, p. 1849, 1967 |
Reactivity Profile |
N,N-DIMETHYL-P-TOLUIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. |
Purification Methods |
Reflux for 3hours with 2 molar equivalents of Ac2O, then fractionally distil it under reduced pressure. Alternatively, dry it over BaO, distil and store it over KOH. The picrate has m 128o (from EtOH). Methods described for N,N-dimethylaniline are applicable here. [Beilstein 12 H 902, 12 III 2026, 12 IV 1874.] |
General Description |
A clear colorless liquid with an aromatic odor. Density 0.937 g / cm3 (Lancaster) and insoluble in water. Hence floats on water. Toxic by skin absorption and inhalation. Flash point 181°F. May release toxic vapors when burned. |
InChI:InChI=1/C9H13N/c1-8-4-6-9(7-5-8)10(2)3/h4-7H,1-3H3
99-97-8 Relevant articles
Additive-free selective methylation of secondary amines with formic acid over a Pd/In2O3 catalyst
Benaissa, Idir,Cantat, Thibault,Genre, Caroline,Godou, Timothé,Pinault, Mathieu
, p. 57 - 61 (2022/01/19)
Formic acid is used as the sole carbon a...
Visible-Light-Induced C(sp2)-C(sp3) Cross-Dehydrogenative-Coupling Reaction of N-Heterocycles with N-Alkyl- N-methylanilines under Mild Conditions
Zhang, Hong-Yu,Chen, Jianjun,Lu, Cong-Cong,Han, Ya-Ping,Zhang, Yuecheng,Zhao, Jiquan
, p. 11723 - 11735 (2021/09/02)
Disclosed herein is a cross-dehydrogenat...
Utilization of renewable formic acid from lignocellulosic biomass for the selective hydrogenation and/or N-methylation
Zhou, Chao-Zheng,Zhao, Yu-Rou,Tan, Fang-Fang,Guo, Yan-Jun,Li, Yang
, p. 4724 - 4728 (2021/09/06)
Lignocellulosic biomass is one of the mo...
Nickel-Catalyzed Amination of Aryl Chlorides with Amides
Li, Jinpeng,Huang, Changyu,Wen, Daheng,Zheng, Qingshu,Tu, Bo,Tu, Tao
supporting information, p. 687 - 691 (2021/01/09)
A nickel-catalyzed amination of aryl chl...
99-97-8 Process route
-
-
97788-15-3
N-benzyl-N,N-dimethyl-p-methylanilinium bromide

-
-
100-39-0
benzyl bromide

-
-
99-97-8
Dimethyl-p-toluidine
Conditions | Yield |
---|---|
In
chloroform;
at 34.9 ℃;
Rate constant;
|
|
In
acetone;
at 45 ℃;
Rate constant;
Equilibrium constant;
|
-
-
67-56-1
methanol

-
-
62-53-3
aniline

-
-
609-72-3
N,N-dimethyl-o-toluidine

-
-
623-08-5
N-methyl-p-toluidine

-
-
121-69-7,77733-26-7
N,N-dimethyl-aniline

-
-
100-61-8
N-methylaniline

-
-
611-21-2
N,2-dimethylaniline

-
-
99-97-8
Dimethyl-p-toluidine
Conditions | Yield |
---|---|
With
monoaluminum phosphate;
at 425 ℃;
Product distribution;
other catalyst, var. temp., var.molar ratio of educts;
|
31.2 % Chromat. 18.3 % Chromat. 5.1 % Chromat. 8.5 % Chromat. 7.0 % Chromat. 10.0 % Chromat. |
99-97-8 Upstream products
-
methanol
-
p-Toluidine hydroiodide
-
4-methylaniline hydrobromide
-
ethanol
99-97-8 Downstream products
-
N-methyl-N-nitroso-p-toluidine
-
4,N,N-trimethyl-2-nitroaniline
-
4-(N-methylacetamido)toluene
-
N-benzyl-N,N-dimethyl-p-methylanilinium bromide
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