623-05-2

  • Product Name:4-Hydroxybenzyl alcohol
  • Molecular Formula:C7H8O2
  • Purity:99%
  • Molecular Weight:124.139
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Product Details

Manufacturer Supply Best Quality 4-Hydroxybenzyl alcohol 623-05-2 with Efficient Transportation

  • Molecular Formula:C7H8O2
  • Molecular Weight:124.139
  • Appearance/Colour:Pink to beige crystalline powder 
  • Vapor Pressure:0.0104mmHg at 25°C 
  • Melting Point:110-112 °C 
  • Refractive Index:1.595 
  • Boiling Point:252 °C at 760 mmHg 
  • PKA:pK1:9.82 (25°C) 
  • Flash Point:145.8 °C 
  • PSA:40.46000 
  • Density:1.22 g/cm3 
  • LogP:0.88450 

4-Hydroxybenzyl alcohol(Cas 623-05-2) Usage

Preparation

Prepared from p-cresol by using the microorganism, Pseudomonas putida.

Flammability and Explosibility

Notclassified

Purification Methods

Crystallise the alcohol from H2O, *C6H6 (m 124o), *C6H6/EtOH or ClCH2CH2Cl (m 122o). [Beilstein 6 III 4546, 6 IV 5909.]

Definition

ChEBI: A member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung.

General Description

4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is as an antioxidant and anti-asthmatic agent.

InChI:InChI=1/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2

623-05-2 Relevant articles

Acute toxicity of benzoic acids to the crustacean Daphnia magna

Kamaya, Yasushi,Fukaya, Yuki,Suzuki, Kyoji

, p. 255 - 261 (2005)

The acute immobilization toxicity of ben...

Selective Synthesis of 4-Hydroxymethylphenol catalysed by Cyclodextrins having Hydroxypropyl Residues

Komiyama, Makoto

, p. 651 - 652 (1988)

The selective synthesis of 4-hydroxymeth...

-

Hutchinson

, (1891)

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Determining Factors for the Product Para/Ortho Ratio and Reaction Rate in the Formation of (Hydroxymethyl)phenols from Phenol and Formaldehyde

Komiyama, Makoto

, p. 2079 - 2082 (1988)

Formations of 2- and 4-(hydroxymethyl)ph...

Discovery of new and highly effective quadruple FFA1 and PPARα/γ/δ agonists as potential anti-fatty liver agents

Cai, Zongyu,Deng, Liming,Geng, Xinqian,Hu, Lijun,Jiao, Shixuan,Li, Zheng,Ren, Qiang,Wang, Bin,Yang, Ying,Zhang, Luyong,Zhou, Zongtao

supporting information, (2021/12/27)

Non-alcoholic fatty liver disease (NAFLD...

Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs)

Linciano, Pasquale,Benedetti, Rosaria,Pinzi, Luca,Russo, Fabiana,Chianese, Ugo,Sorbi, Claudia,Altucci, Lucia,Rastelli, Giulio,Brasili, Livio,Franchini, Silvia

, (2020/11/24)

Histone Deacetylases (HDACs) are among t...

Hydroboration Reaction and Mechanism of Carboxylic Acids using NaNH2(BH3)2, a Hydroboration Reagent with Reducing Capability between NaBH4and LiAlH4

Wang, Jin,Ju, Ming-Yue,Wang, Xinghua,Ma, Yan-Na,Wei, Donghui,Chen, Xuenian

, p. 5305 - 5316 (2021/04/12)

Hydroboration reactions of carboxylic ac...

Ambient-pressure highly active hydrogenation of ketones and aldehydes catalyzed by a metal-ligand bifunctional iridium catalyst under base-free conditions in water

Wang, Rongzhou,Yue, Yuancheng,Qi, Jipeng,Liu, Shiyuan,Song, Ao,Zhuo, Shuping,Xing, Ling-Bao

, p. 1 - 7 (2021/05/17)

A green, efficient, and high active cata...

623-05-2 Process route

bis-(2-phenylacetylamino-ethyl)-carbamic acid 4-nitro-phenyl ester
757967-03-6

bis-(2-phenylacetylamino-ethyl)-carbamic acid 4-nitro-phenyl ester

phenylacetic acid
103-82-2

phenylacetic acid

2-aminoethylimidazolidone
6281-42-1

2-aminoethylimidazolidone

4-nitro-phenol
100-02-7,78813-13-5,89830-32-0

4-nitro-phenol

(4-hydroxyphenyl)methanol
623-05-2

(4-hydroxyphenyl)methanol

carbon dioxide
124-38-9,18923-20-1

carbon dioxide

Conditions
Conditions Yield
With water; penicillin-G-amidase; In Chremephor EL; dimethyl sulfoxide; at 37 ℃; pH=7.4; Kinetics; Enzymatic reaction; Aqueous phosphate buffer;
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl 4-(bis(benzyloxy)methyl)phenylcarbamate
1349832-78-5

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl 4-(bis(benzyloxy)methyl)phenylcarbamate

4-aminobenzaldehyde
556-18-3,28107-09-7

4-aminobenzaldehyde

(4-hydroxyphenyl)methanol
623-05-2

(4-hydroxyphenyl)methanol

C<sub>14</sub>H<sub>13</sub>NO<sub>2</sub>
1286727-45-4

C14H13NO2

C<sub>21</sub>H<sub>19</sub>NO<sub>3</sub>
1286727-47-6

C21H19NO3

benzyl alcohol
100-51-6,185532-71-2

benzyl alcohol

Conditions
Conditions Yield
With urea hydrogen peroxide adduct; In water; acetonitrile; at 25 ℃; for 3h; pH=8; aq. phosphate buffer;

623-05-2 Upstream products

  • 120-47-8
    120-47-8

    Ethyl 4-hydroxybenzoate

  • 836-43-1
    836-43-1

    4-benzyloxybenzyl alcohol

  • 2316-62-3
    2316-62-3

    3,5-dibromo-4-hydroxybenzyl alcohol

  • 50-00-0
    50-00-0

    formaldehyd

623-05-2 Downstream products

  • 5355-17-9
    5355-17-9

    4-hydroxybenzyl methyl ether

  • 2937-61-3
    2937-61-3

    2,4,6-tris(hydroxymethyl)phenol

  • 57726-26-8
    57726-26-8

    4-hydroxybenzyl ethyl ether

  • 2937-64-6
    2937-64-6

    4-(acetyloxy)benzyl acetate