53936-56-4
- Product Name：Deoxyarbutin
- Molecular Formula：C11H14O3
- Purity：99%
- Molecular Weight：194.23
Product Details
Quality products make an important contribution to long-term revenue and profitability. Factory Sells Best Quality Deoxyarbutin 53936-56-4 with USP
1.What is the Deoxyarbutin ?
Deoxyarbutin acts as a skin whitening agent through the inhibition of tyrosinase. A safer alternative to the use of hydroquinone and arbutin.
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-
110-87-2
3,4-dihydro-2H-pyran
-
-
123-31-9,8027-02-9
hydroquinone
-
-
53936-56-4
4-(tetrahydro-2H-2-pyranyloxy)phenol
| Conditions | Yield |
|---|---|
|
With
ruthenium(III) acetate;
at 20 ℃;
for 12h;
|
72% |
|
With
pyridinium p-toluenesulfonate;
In
dichloromethane;
at 10 - 25 ℃;
for 16h;
Inert atmosphere;
|
52.7% |
|
With
pyridinium p-toluenesulfonate;
In
tetrahydrofuran;
at 20 ℃;
for 16h;
Inert atmosphere;
|
49.6% |
|
toluene-4-sulfonic acid;
In
diethyl ether;
Inert atmosphere;
|
43% |
|
With
toluene-4-sulfonic acid;
In
tetrahydrofuran; dichloromethane;
at 20 ℃;
for 16h;
|
38% |
|
With
pyridinium p-toluenesulfonate;
In
acetone;
at 20 ℃;
for 144h;
Inert atmosphere;
|
29% |
|
pyridinium p-toluenesulfonate;
In
diethyl ether; dichloromethane;
|
|
|
With
pyridinium p-toluenesulfonate;
In
diethyl ether; dichloromethane;
at 20 ℃;
for 3h;
|
|
|
With
poly(4-vinylpyridine) supported copper(II) oxide nanoparticles;
In
dichloromethane;
at 20 ℃;
for 0.0833333h;
chemoselective reaction;
|
-
-
53936-79-1
4-benzyloxyphenyl 2-tetrahydropyranyl ether
-
-
53936-56-4
4-(tetrahydro-2H-2-pyranyloxy)phenol
| Conditions | Yield |
|---|---|
|
With
5%-palladium/activated carbon; hydrogen;
In
ethanol;
at 20 ℃;
for 3h;
under 3000.3 Torr;
Autoclave;
|
100% |
|
With
aluminum oxide; hydrogen;
palladium on activated charcoal;
In
ethyl acetate;
at 20 ℃;
Product distribution / selectivity;
|
82% |
|
With
hydrogen; calcium carbonate;
palladium on activated charcoal;
In
ethyl acetate;
at 20 ℃;
Product distribution / selectivity;
|
80% |
|
With
hydrogen; sodium carbonate;
palladium on activated charcoal;
In
isopropyl alcohol;
at 20 ℃;
Product distribution / selectivity;
|
80% |
|
With
hydrogen; calcium carbonate;
palladium on activated charcoal;
In
ethanol; ethyl acetate;
at 20 ℃;
Product distribution / selectivity;
|
80% |
|
With
hydrogen; calcium carbonate;
palladium on activated charcoal;
In
ethanol;
at 20 ℃;
Product distribution / selectivity;
|
78% |
|
With
hydrogen; calcium carbonate;
palladium on activated charcoal;
In
isopropyl alcohol;
at 20 ℃;
Product distribution / selectivity;
|
77% |
|
With
pyridine; 5%-palladium/activated carbon; hydrogen;
In
tetrahydrofuran; ethanol;
at 50 ℃;
for 8h;
under 3750.38 Torr;
|
4.1 g |
|
With
5%-palladium/activated carbon; hydrogen;
In
tetrahydrofuran; ethanol;
at 50 ℃;
for 8h;
under 3750.38 Torr;
|
8.8 g |
|
With
5%-palladium/activated carbon; hydrogen;
In
tetrahydrofuran; ethanol;
at 50 ℃;
for 8h;
under 3750.38 Torr;
|
8.8 g |
|
With
5%-palladium/activated carbon; hydrogen;
In
tetrahydrofuran; ethanol;
at 50 ℃;
for 8h;
under 3750.38 Torr;
|
8.3 g |
|
With
5%-palladium/activated carbon; hydrogen;
In
tetrahydrofuran; ethanol;
at 50 ℃;
for 8h;
under 3750.38 Torr;
Sealed tube;
|
8.8 g |
2.What is the CAS number for Deoxyarbutin ?
The CAS number of Deoxyarbutin is 53936-56-4.
More information of Deoxyarbutin 53936-56-4 are:
|
CAS Number |
53936-56-4 |
|
Density |
1.174 g/cm3 |
|
Melting Point |
83-88℃ |
|
Boiling Point |
349.779 °C at 760 mmHg |
|
Flash Point |
165.341 °C |
|
HS CODE |
2938909090 |
|
PSA |
38.69000 |
|
LogP |
2.29760 |
|
Pka |
10.10±0.15(Predicted) |
3.What are another words for Deoxyarbutin ?
Synonyms for Deoxyarbutin 53936-56-4:4-(Tetrahydro-2H-pyran-2-yloxy)phenol;
4.What is the molecular formula of Deoxyarbutin?
The chemical formula of Deoxyarbutin is C11H14O3 which containing 11 Carbon atoms,14 Hydrogen atoms and 3 Oxygen atoms,and the molecular weight of Deoxyarbutin is 194.23.
5.What is Deoxyarbutin (53936-56-4) used for?
Deoxyarbutin is a tyrosinase inhibitor (IC50 = 17.5 μM for mushroom tyrosinase). It reduces melanin content in isolated dark human melanocytes when used at a concentration of 1.56 μM. Topical administration of deoxyarbutin (5%) induces skin lightening in human skin mouse xenograft models. Deoxyarbutin also inhibits proliferation of B16/F10 murine melanoma cells (EC50 = 39.56 μM). It induces apoptosis and halts the cell cycle at the S phase in B16/F10 cells when used at a concentration of 50 μM. Deoxyarbutin (50 mg/kg) reduces tumor growth in a B16/F10 murine melanoma model.
Relevant articles related to Deoxyarbutin:
|
Article |
Source |
|
POLYMERIZABLE CINNAMATE ESTER DERIVATIVE MANUFACTURING METHOD |
- Paragraph 0121-0122; 0127, (2020/08/15) |
|
Method for producing 2-hydrazinobenzothiazole derivative also providing a polymerizable composition which is useful for producing a film-like polymer |
- Paragraph 0150; 0152; 0161, (2019/09/04) |
6.Buy Deoxyarbutin with the best price .
Hubei Shengliyuan New Materials Co., Ltd is a quality supplier of Deoxyarbutin. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Deoxyarbutin 53936-56-4.
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